Effective pain management requires the right attitudes, judgments, skills, and knowledge that have an impact on pain treatment outcomes. A careful assessment of each individual's pain sensitivity is invaluable for the prevention, evaluation, and treatment of pain. This study aimed to describe nurses' knowledge and attitude toward pain management, to describe the nurses' personal pain sensitivity, and to determine the relationship between nurses' knowledge and attitude level toward pain sensitivity level. The method used in this research is a cross-sectional study with a survey design that provides a quantitative picture of pain sensitivity, knowledge, and attitudes towards pain management using KARSP and PSQ questionnaires with validity value (r>0.8), and the internal consistency, or reliability, using Cronbach's alpha has been measured (>0.7). The population are nurses who work in one of the private hospital in Bandar Lampung with participated sample are 160 nurses. The results show that the majority are lack of knowledge regarding paint management. It is indicated that 96.87% of the nurses lack knowledge with an average of 48,89. Pain sensitivity is catego rized as moderate level. It is found that there is a relationship be tween knowledge and attitude with educational level with a sig 0.017 (P0.05). Efforts to improve knowledge, attitudes, skills and pain sensitivity among healthcare professionals are needed, monitored and evaluated by the hospital administration to improve nurses' skills in pain management for better patient outcomes. Moreover, training or in-service education is very important to increase the knowledge and attitude of the nurses toward pain management. It is recommended that future researchers compare the nurses' pain sensitivity and the patient's pain sensitivity toward the patient's satisfaction with pain management.